TetX 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in ELISA, WB, InhA 和 Neut. Suitable for Clostridium tetani.
Quick Overview for TetX 抗体 (ABIN7232855)
抗原
TetX
适用
Clostridium tetani
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Inhibition Assay (InhA), Neutralization (Neut)
克隆位点
B416M
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原理
- Anti-Clostridium tetani Toxin Mouse Monoclonal Antibody
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特异性
- This antibody recognizes C. tetani toxin.
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交叉反应
- Clostridium tetani
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免疫原
- Toxin purified from culture filtrate of C. tetani.
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亚型
- IgG1
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应用备注
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ELISAImmunoblotting A band of ~150,000 is detected.
End users should determine optimal dilutions for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- This antibody is stable at 4°C for short-term storage and for at least one (1) year at -20° to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
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- TetX
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背景
- Tetanus toxin,Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.,Clostridium tetani is an anaerobic, gram-positive, spore-forming rod found in soil and in the intestinal tracts and feces of animals. Most cases of tetanus result C. tetani spores entering small puncture wound. Infections remain localized, but systemic damage results from the production of exotoxins that are released when the spores germinate and grow. Tetanus toxin â€Tetanospasmin†is one of the most potent toxins known, third only to botulinum toxin and diphtheria toxin. This potent neurotoxin enters peripheral nerves and travels to the central nervous system where it interferes with the release of neurotransmitters, causing muscle contraction and spasm.
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UniProt
- P04958
抗原
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